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☐ ☆ ✇ Nature

Cryo-EM structure of the transposon-associated TnpB enzyme

By: Ryoya Nakagawa · Hisato Hirano · Satoshi N. Omura · Suchita Nety · Soumya Kannan · Han Altae-Tran · Xiao Yao · Yuriko Sakaguchi · Takayuki Ohira · Wen Y. Wu · Hiroshi Nakayama · Yutaro Shuto · Tatsuki Tanaka · Fumiya K. Sano · Tsukasa Kusakizako · Yoshiaki Kise · Yuzuru — April 5th 2023 at 00:00

Nature, Published online: 05 April 2023; doi:10.1038/s41586-023-05933-9

Cryo-electron microscopy analysis of the Deinococcus radiodurans ISDra2 TnpB in complex with its cognate ωRNA and target DNA provides insights into the mechanism of TnpB function and the evolution of CRISPR–Cas12 effectors.
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