Spatially resolved single-cell translatomics at molecular resolution | Science

RIBOmap enables single-cell in situ profiling of mRNA translation in 3D for thousands of genes in intact cells and tissues.

Virus-like transposons cross the species barrier and drive the evolution of genetic incompatibilities | Science

Mavericks, virus-like transposons, gained a fusogen in nematodes and became a recurrent vector of horizontal gene transfer.

News at a glance: Muscular dystrophy therapy, lab-grown chicken, and humans’ toll on wildlife

The latest in science and policy

Will Canada permit killer whale extinction? | Science

HomeScienceVol. 380, No. 6652Will Canada permit killer whale extinction?Back To Vol. 380, No. 6652 Full accessLetter Share on Will Canada permit killer whale extinction?Misty MacDuffee [email protected], Lance Barrett-Lennard, [...] , Auston Chhor, Allison M. Dennert, [...] , Peter S. Ross, David C. Scott, Valeria Vergara, and Kristen Walters+5 authors +3 authors fewerAuthors Info & AffiliationsS…

Border conservation in Hindu Kush-Himalaya | Science

The Hindu Kush-Himalaya region (HKH) is one of the most biodiverse places in the world. The area hosts four global biodiversity hotspots (1) as well as 12 terrestrial and 5 freshwater Global 200 Ecoregions (2), yet multiple species are at risk of imminent extinction (3). Both physical barriers and policy differences across international borders hinder conservation efforts. Protecting the region’s biodiversity will require multilateral cooperation.

A family’s pride in educated daughters | Science

HomeScienceVol. 380, No. 6652A family’s pride in educated daughtersBack To Vol. 380, No. 6652 Full accessLetterPast as Prologue Share on A family’s pride in educated daughtersQura Tul Ain [email protected]Authors Info & AffiliationsScience29 Jun 2023Vol 380, Issue 6652p. 1331DOI: 10.1126/science.adi2884 PREVIOUS ARTICLEBorder conservation in Hindu Kush-HimalayaPreviousNEXT ARTICLEIn Science Journ…

Not teaching evolution is an injustice | Science

Since April, India has been roiled by controversy around the excision of several topics, including evolution and the periodic table, from school textbooks (up to grade 10) by the National Council for Educational Research and Training (NCERT). This was ...

A new class of antiparasitic drugs | Science

Cyanotriazole compounds “poison” topoisomerase II of pathogenic trypanosomatids

Staving off cell death | Science

A signaling pathway that senses energy stress opposes necroptotic cell death

Mapping RNA translation | Science

A new method maps the location of thousands of translating RNAs in cells and tissues

Observation of high-energy neutrinos from the Galactic plane | Science

Astrophysical neutrinos are emitted from the plane of the Milky Way galaxy, implying the presence of nearby sources.

Emissions and energy impacts of the Inflation Reduction Act | Science

Economy-wide emissions drop 43 to 48% below 2005 levels by 2035 with accelerated clean energy deployment

Agricultural expansion raises groundwater and increases flooding in the South American plains | Science

Converting plains to agriculture creates shallow water tables and increased flooding at the subcontinent scale.

Thalidomide in America | Science

A journalist corrects the record on US exposure

In Other Journals | Science

Editors’ selections from the current scientific literature

Galactic neutrinos in the Milky Way | Science

A source of neutrinos may lie within the midplane of the Galaxy

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1 | Science

Protein kinases control a metabolic checkpoint that dictates cell responses to metabolic stress.

Observation of Rydberg moiré excitons | Science

Moire superlattices can be used to spatially confine and manipulate Rydberg excitons.

Gullies on Mars could have formed by melting of water ice during periods of high obliquity | Science

Simulations of Mars’ past climate show that water could have been a liquid at the locations where gullies formed.

Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome | Science

Encounter times of chromosomal DNA loci are much less dependent on genomic distance than predicted by existing polymer models.