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Are We Not Doing Enough Drugs?

“To admit to any intention to use chemical substances, whether found in nature or synthesized in laboratories, in the aim of changing one’s apprehension of reality, is to leave the guild of the philosophers behind, with all its constricting norms and shibboleths, and to join the company, over in the deep end of the pool of life, of sundry countercultural weirdos and deviants.”

So writes Justin E. H. Smith (University of Paris 7 – Denis Diderot) in an article in Wired, in which he discusses, in his characteristically erudite manner and enviably delightful prose, his use of psychedelic drugs.

[detail of painting by Kelsey Brooks, from “Party Drugs” exhibit]

He continues:

This shows, I think, just how conservative philosophy remains, in some respects, as an academic discipline. At a cultural moment when psychedelics are getting a second wind, and even someone as upstanding as Michael Pollan has moved from counseling us to eat our roughage to praising the benefits of microdosing, philosophers are conducting themselves as though it were still 1950, when we wore skinny ties to colloquia, got funding from the RAND Corporation to work on decision trees and other such narrow and straitlaced endeavors, and all knew that it is the unaltered and wakeful mind that has exclusive access to the forms and qualities of the external world.

Yet we don’t know any such thing:

For all our efforts, we still are not one step closer to apprehending the things in themselves. It is not that science hasn’t progressed—of course it has—but rather that the problem is conceptual and not empirical. You can’t perceive the thing that lies behind what you are perceiving, since the instant you do perceive it, it no longer lies behind but is front and center. Given what appears to be this logically necessary stalemate between us and the world, it seems inevitable that alternative accounts of the fundamental nature of reality—alternative ontologies, as we say—should keep returning and drawing off at least some philosophers who get fed up with an external world that demands our loyalty yet refuses to show itself.

In at least some of these alternative ontologies, the visions that come to us unbidden, in the liminal states of insobriety, hypnagogia, or theurgic ecstasy, are not to be dismissed out of hand as obstacles to our apprehension of truth, but may in fact be vehicles of truth themselves. 

And so we get this professionally- and self-aware “confession” and recommendation:

I am aware I’m pushing up against the limits of respectability dictated by the implicit norms of my discipline, but I’ve gone about as far as I was ever destined to go in the ranks of this guild, and I’ve got nothing, and no one, to be afraid of. So I’m just going to come right out and say it: I am a philosopher who has taken an interest, of late, in psychedelic experimentation, and I find that my experiments have significantly widened the range of accounts of the nature of reality that I am disposed to take seriously. If you think you are in an emotional state to handle it, and in a legal jurisdiction that permits it, and you think you might benefit from being jolted out of your long-held ontological commitments, then I would recommend that you try some psychotropic drugs as well.

What’s to be gained? Perhaps more of that thing philosophy is most certain to produce: uncertainty. Smith says:

I am significantly less cocky now, my cluelessness is more evident to me, a constant that accompanies me in each moment of the day. No one seems more pathetic to me, now, in their own cluelessness, than the self-styled “realists” who prejudicially and without any grounds go on supposing that they have a firm grasp of concepts like “nature,” “matter,” “being,” “thing,” “world,” “self,” that this grasp flows directly from their acceptance of the plain evidence of reason buttressed by empirical discovery, and that the question of how many kinds of being there are, and of the nature of these beings, is one that has been definitively settled over the past few centuries of naturalistic inquiry…

While I remain as uncertain as ever about the ultimate structure of the world, I also have new inclinations, and new sympathies, toward accounts of it that had previously struck me as altogether off the table. That widening is itself a sort of newfound knowledge, even if it contains no new certainties.

Smith shares how some of the insights he has gained or developed while experimenting with drugs. Understanding how far out he might sound to the rest of us—while the article appears in Wired, it does seem like he is writing especially to his fellow philosophers—he voices, and answers, some skeptical questions:

Are any of these lucubrations to be taken at all seriously? Or do they just describe how the world appears to one sorry fellow who’s got a “brain on drugs”? (Readers of a certain age will at this point picture an egg in a frying pan.) Well yes, of course it’s a brain on drugs, but this just returns us to the original problem: Your brain is always on drugs. That is, there is always a neurochemical correlate to any of your conscious perceptions whatsoever. You might be tempted to say that supplementing gets in the way of correct perception, and that the only reliable way of apprehending the world as it is must depend only on the default setting of the mind, with no extras. But again, even this setting delivers us delirious hallucinations for about eight hours out of each 24. Moreover, it is hard to conceive of any valid argument against supplementation…

Read the whole thing here.

Smith is not the only philosopher who has been paying attention to psychedelics lately. Chris Letheby (University of Western Australia) authored Philosophy of Psychedelics, published by Oxford University Press in 2021, as well as a number of articles about psychedelics (for example, he makes points about the possible epistemic benefits of psychedelics in his 2016 “The Epistemic Innocence of Psychedelic States“). Last year saw the publication of Philosophy and Psychedelics: Frameworks for Exceptional Experience (Bloomsbury), a collection edited by Christine Hauskeller and Peter Sjöstedt-Hughes (Exeter). This year, a collection edited by Letheby and Philip Gerrans (Adelaide), Philosophical Perspectives on the Psychedelic Renaissance, is due out from Oxford.

Discussion welcome.


Related: Philosopharmacology

Man takes a drug-free "psychedelic trip" and is pleasantly surprised to discover it doesn't suck

Los Angeles Times writer Adam Tschorn wrote about his hour-long session at the Reality Center in Santa Monica. For $249, customers receive a multi-sensory experience that is supposed to be something like a shroom trip. With a couple of psilocybin experiences under his belt, Tschorn was able to compare his past trips with the Reality Center's drug-free session. — Read the rest

New mechanism proposed for why some psychedelics act as antidepressants

Image of a multi-color, iridescent mushroom.

Enlarge (credit: VICTOR de SCHWANBERG/SCIENCE PHOTO LIBRARY)

Psychedelic drugs are often used for entertainment purposes. But there have been some recent indications that they can be effective against PTSD and treatment-resistant depression. Figuring out whether these substances work as medicinal drugs can be challenging because (as one researcher helpfully pointed out) it's difficult to do a controlled experiment when it's easy to figure out who's in the treatment group. Still, we've made some progress in understanding what's happening with psychedelics at the molecular level.

Many psychedelics seem to bind to a specific receptor for the neural-signaling molecule serotonin, activating it. That would seem to make sense for antidepressive effects, given that many popular antidepressants also alter serotonin signaling (such as in SSRIs, or selective serotonin reuptake inhibitors). But SSRIs don't produce any of the mind-altering effects that drive non-medical interest in psychedelics, so things remain a bit confusing.

New data suggests that psychedelics may activate serotonin signaling in a very different way than serotonin itself can, reaching the receptors in parts of the cell that serotonin can't get to.

Read 11 remaining paragraphs | Comments

The Top 5 Longreads of the Week

A bowl of bright orange macaroni and cheese, photographed from above, against a deep blue background

As January draws to a close, our favorite stories this week included a stirring critical essay, a paean to the world’s greatest boxed meal, a rethinking of psychedelics’ impact on the planet, a profile of a craftsperson at his peak, and an eye-opener about how humpback whales use air in some unexpected ways.

1. Corky Lee and the Work of Seeing

Ken Chen | n+1 | 11,542 words | January 25, 2023

After Corky Lee passed last year, the photographer and community organizer was memorialized in his hometown’s most conventionally prestigious outlets: The Times offered a sizable obituary, as did Hua Hsu in The New Yorker. This week, on the first anniversary of Lee’s death, Ken Chen rendered an altogether different kind of portrait in n+1. Much of the same biographical information is included, as are a number of Lee’s iconic photographs of Asian Americans in New York throughout the last six decades. Yet, when Chen writes about his encounters with Lee, and about the 14 photographs he selects to represent Lee’s work, the grief that suffuses his words isn’t solely about Lee, but about the many atrocities visited upon the Asian American community, up to and after Lee’s death. Chen’s critical acumen here is reason enough to read: “His images lack a charismatic subject,” he writes of Lee. “Those whom capital dismissed as surplus, he saw as beautiful. He commemorated the multitude, the striking waiters and seamstresses whose unruly abundance crowded away any beatific composition.” But he brings a similar understated poetry to the social conditions Lee’s work served to illuminate — and with violence against Asian American elders and others seemingly unending (including a horrifying recent attack in my own hometown), that juxtaposition makes Chen’s piece nearly as indelible as the images it contains. —PR

2. An Ode to Kraft Dinner, Food of Troubled Times

Ivana Rihter | Catapult | January 19, 2023 | 2,261 words

I only discovered Kraft dinners later in life after moving to North America revealed the cult of Kraft to me. A stable lurking in every cupboard; I admired the respect that something so impossibly orange had managed to garner. When Ivana Rihter finds KDs, though, they are much more; cooked for her by her baba, they are inextricably linked to her immigration story. She describes the process of boiling the pasta and adding the sauce with reverence, the memory mixed in with her love for her baba and appreciation for the economic hardships her family struggled through to start their new life. Her baba teaches her to put feta on top, and with this “secret little piece of the home country mixed in with all-American shelf-stable cheese” it remains a food for life, and — consistently sitting at about a dollar a box — one that carries on seeing her through hard times. I found this an unexpectedly beautiful essay, more about memory and belonging than cheesy pasta. Food can transport you back in time, especially if, as Rihter describes it, it “is soaked with memories of [an] origin story.” —CW

3. Tripping for the Planet: Psychedelics and Climate Activism

Amber X. Chen | Atmos | January 16, 2023 | 3,196 words

In this piece, Chen explores what the current psychedelic renaissance means for environmental activism, and how synthetic drugs like LSD and MDMA and psychoactive plants like ayahuasca and peyote can stir change within individuals — and ultimately galvanize social movements. This all sounds incredibly positive on the surface, but not everyone who dabbles in such mind-altering journeys is transformed for the better; psychedelics also fuel right-wing movements, too. (See: “QAnon Shaman.“) The decriminalization of psychedelics is a step toward making their therapeutic benefits accessible to more people, yes, but as Chen notes, it increases the threat of deforestation, and — with today’s psychedelic movement being largely white — it also takes power away from Indigenous people, who have harnessed the healing power of these sacred plants for thousands of years. (See also a Top 5 essay I picked last year: “The Gentrification of Consciousness.”) I appreciate Chen’s exploration here, and the questions posed that I haven’t stopped thinking about, like: “How broken is Western society that we think we need drugs in order to facilitate mass climate action?” —CLR

4. The Violin Doctor

Elly Fishman | Chicago Magazine | January 17, 2023 | 4,177 words

Recently, in his late 60s, my dad decided to learn how to play the violin. I respect the choice to try the impossible, especially something as delicate and timeless as bowing a stringed instrument. (My parents’ cats, who endure the scratching out of notes from beneath the couch or bed, seem to have a different opinion.) After reading this lovely profile, I think perhaps my dad, a skilled carpenter, should also try apprenticing as a luthier. I, someone with zero skills at playing an instrument besides an egg shaker, who curses putting IKEA furniture together, was mesmerized by the descriptions of how John Becker, perhaps the best violin restorer on earth, practices his craft. Elly Fishman’s profile has a musical quality: It sweeps readers through chapters of Becker’s personal story and dwells in long, lyrical moments when, with the surest of hands, Becker repairs some of the most revered instruments on the planet — namely, Stradivari. There are just 650 of the violins left. What makes them so extraordinary? Musicians and scientists may puzzle over that question forever. In the meantime, Becker works — quietly, meticulously, instinctively. “We are caretakers of these instruments,” one of his clients tells him. “We move on, but these instruments continue to the next generation.” —SD

5. For Humpbacks, Bubbles Can Be Tools

Doug Perrine | Hakai Magazine | December 20, 2022 | 1,500 words

It’s well known that many animals use tools to aid feeding and other tasks of life. Think: otters floating on their backs, cracking shells with rocks. You’d think it would be hard for whales to use tools, but as Doug Perrine reports at Hakai Magazine, humpbacks use what’s available to them — air and water — to form bubbles for a variety of activities. “I’m tempted to describe the air in a humpback’s lungs as a Swiss army knife because I’ve seen whales do so many different things with it,” he wrote. “It is not actually a tool collection though, but a storehouse of raw construction material with which the whale can fashion a variety of tools. Lacking free fingers and opposable thumbs, whales are unable to create and use tools in the same way as humans, but reveal their intelligence through the manner in which they utilize other body parts for tool production and use.” —KS


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Tripping for the Planet: Psychedelics and Climate Activism

The human fascination with psychedelics is nothing new. The earliest use of psychoactive plants dates back to 11,000 B.C. in Israel, with the brewing of beer, while some people theorize that the eating of magic mushrooms 20,000 years ago fostered the intellectual evolution of early humans (see: “stoned ape theory“). For Atmos, Amber X. Chen explores the current psychedelic renaissance’s effects on environmental activism, and how hallucinogenic drugs like LSD and psilocybin, and ancient plant medicine like ayahuasca, can stir change within individuals — and ultimately galvanize social movements.

It sounds incredibly positive on the surface, but not everyone who dabbles in such mind-altering journeys comes out the other side positively transformed. As research shows, psychedelics have enormous therapeutic potential, sure, but they also fuel right-wing movements, too (see: “‘QAnon Shaman“).

The use of psychoactive plants has its roots with Indigenous tribes, who’ve used them for healing and cultural practices for thousands of years. Before we push for the decriminalization of psychedelics and encourage their use to help stir climate activism, reports Chen, there are steps that need to be taken for these powerful, sacred plants to play a positive role in the environmental movement.

In a 2022 study that surveyed 240 people, mostly from Australia, the U.S., and the U.K., who had prior experience with psychedelics, researchers found more pro-environmental behaviors among participants who reported having had a previous mystical experience than those who had not. The researchers measured these behaviors based on a wide range of behaviors—anything from adopting a vegetarian diet and purchasing eco-friendly products to turning off your lights more regularly.

Before adding psychedelics to the climate action toolkit, we need to first plan for their conservation, prioritize Indigenous cultures, and place Indigenous peoples into leadership positions. This means respecting the wishes of Indigenous peoples: if a tribe or nation doesn’t want its plant medicines commercialized, we should not interfere. For those willing to share, we must not appropriate. Ultimately, we have to listen.

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