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Rapid weight loss may improve advanced fatty liver disease — new research

Our recent study has shown that the “soups and shakes” diet may be able to reduce the severity of liver disease

Fiber is your body’s natural guide to weight management

". . . consider putting the carbs back in their fiber wrappers. It's hard to improve upon nature's design"

Unsolved Wendy’s outbreak shows challenges of fighting foodborne illnesses

A Wendy's old-fashion burger. Romaine lettuce on Wendy's burgers is thought to be the cause of the outbreak.

Enlarge / A Wendy's old-fashion burger. Romaine lettuce on Wendy's burgers is thought to be the cause of the outbreak. (credit: Getty | Francis Dean)

We will never know for certain what caused a large, multistate outbreak of E. coli O157:H7 infections linked to Wendy's restaurants late last year, according to a new study led by investigators at the Centers for Disease Control and Prevention.

The study, highlighting weaknesses in our ability to respond to foodborne outbreaks, lands amid a separate report published by the CDC finding that, in general, we're also failing to prevent outbreaks. In fact, cases from some common foodborne pathogens have increased relative to pre-pandemic levels.

In the outbreak last year, which spanned from July to August, at least 109 people in six states fell ill, with 52 needing to be hospitalized. Eating at Wendy's was a clear link. But it wasn't enough to crack the case.

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Buy Charles Schulz's home/studio in Sonoma County

The Sebastopol, California, home that Charles Schulz used as his office and studio from the mid-1960s to the early 1970s is up for sale, for almost $4 million.

It looks like a beautiful, but small (one bedroom, which had been Schulz's studio) home, in a stunning setting. — Read the rest

Blocked artery in your leg? Here’s what you should know

ProPublica analyzed artery procedures and found that some doctors are making millions doing questionable treatments

Making risotto is so much easier than you think

No more risotto gatekeeping! While it may require a little extra time, risotto can still be a weeknight meal

Death toll rises to 7 in fungal meningitis outbreak; cases at 34, 161 at risk

One of the medical clinics suspended by Mexican health authorities in Matamoros, Tamaulipas, Mexico, on May 19, 2023.

Enlarge / One of the medical clinics suspended by Mexican health authorities in Matamoros, Tamaulipas, Mexico, on May 19, 2023. (credit: Getty | AFP)

Three more people in the US have died from fungal meningitis in an outbreak linked to tainted surgeries in Mexico, bringing the total deaths to seven, the Centers for Disease Control and Prevention reported Thursday.

The total case count remains unchanged from an update earlier this month, with 34 cases in the US: nine confirmed, 10 probable, and 15 suspected. Health officials are investigating 161 others who may have been exposed.

The outbreak is linked to cosmetic surgeries involving epidural anesthesia at two clinics in Matamoros, Mexico, just across the border from Brownsville, Texas. Mexican and US officials suspect that a component of the anesthetic was contaminated, resulting in the pathogenic fungus Fusarium solani being injected directly into people's spinal cords. The tainted surgeries are thought to have occurred between January 1, 2023, to May 13, 2023, around when the clinics were shut down by local health officials.

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Deals: Get the 15-Inch MacBook Air for Record-Low Price of $1,199 ($100 Off)

Apple's brand-new 256GB 15.3-inch MacBook Air is back down to $1,199.00 on Amazon today, from its original price of $1,299.00. We've seen this sale one time previously in the middle of June, and it remains the best deal tracked yet on the latest MacBook Air.

Note: MacRumors is an affiliate partner with Amazon. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.

This sale is available in three of the four colors: Midnight, Space Gray, and Starlight. All three models are in stock, but there are varying delivery dates among them. Midnight and Space Gray have the fastest delivery estimates of around July 2, although Space Gray stock is dwindling. Starlight models are currently being quoting delivery of around July 9–11.



This time around, we aren't tracking any notable discounts on the 512GB models. Head to our full Deals Roundup to get caught up with all of the latest deals and discounts that we've been tracking over the past week.
Related Roundup: Apple Deals

This article, "Deals: Get the 15-Inch MacBook Air for Record-Low Price of $1,199 ($100 Off)" first appeared on MacRumors.com

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Canceling Equity

Who's afraid of promoting "equity" in public health?

Watch the Skies: A UFO Believers Reading List

A billboard with a drawing of a UFO and the words ALIEN PARKING, with an arrow

This story was funded by our members. Join Longreads and help us to support more writers.

Long before the 1947 Roswell incident brought “little green men” into the public consciousness and prompted an explosion in UFO sightings, writers and scientists have speculated about the existence of life beyond our planet. H. G. Wells laid the groundwork for modern science fiction with novels like The War of the Worlds (1898), one of the first books to imagine an extraterrestrial invasion. Before Wells, Italian astronomer Giovanni Schiaparelli (1835-1910) sparked the imagination by discovering “canals” on Mars. But for the first recorded instance of humanity pondering the possibility of alien life, we have to go all the way back to ancient Greek and Roman times. In the first century B.C., Roman poet Lucretius wrote, “Nothing in the universe is unique and alone and therefore in other regions there must be other earths inhabited by different tribes of men and breeds of beast.” Not exactly a controversial supposition; still, whether or not such tribes have come to our planet remains impossible to prove, and those who claim to have encountered alien beings have long been dismissed.

That said, in recent years, the concept of otherworldly visitors has begun to shift toward the mainstream. In 2022, the U.S. Department of Defense established the All-domain Anomaly Resolution Office, the latest governmental entity devoted to investigating unexplained sightings. Even the term of choice, “UFO,” has given way to “UAP”—unidentified aerial (or anomalous) phenomenon. And just this June, former U.S. Air Force officer and intelligence official David Grusch claimed that the U.S. government had retrieved remains of several aircraft of “non-human” origin. The fallout from Grusch’s claims is yet to be determined—as is their veracity—but it seems likely that, in the end, the world will settle back into the binary of believers and skeptics, with no concrete evidence to settle the debate. Regardless of which camp you fall into, some of us will always look skyward with hope; we may never be able to scour the entirety of the universe, but it’s hard not to thrill to Lucretius’ logic. In the meantime, the longform articles collected here offer a fascinating glimpse into the UFO community and the stories that have shaped our modern understanding of the topic.

I Want To Believe (Brad Badelt, Maisonneuve, July 2021)

For me, what makes alleged alien encounter testimony so compelling is that—regardless of whether I believe the person’s interpretation of events—the incident had an undeniable and profound effect on their lives. This may not be true in every case, but even if you write off many accounts as delusion or whimsy or simply fiction, you’re still left with a legion of people who have been dramatically changed by their perceived experiences. It’s comforting to know, then, that for those such as Jason Guillemette, a character in this piece about amateur ufologists, communities exist where one can share their experiences without judgment.

In Guillemette’s case, that community is the Mutual UFO Network (MUFON), a non-profit, volunteer-run organization active in more than 40 countries—and one whose members are as rigidly skeptical as Guillemette. For most MUFON alumni, this is a quest for truth, not validation; members work rigorously to find earthly explanations for reported sightings. And as Badelt widens his scope to other folks in other organizations, you can’t help but be moved by people’s stories. After all, if you were to have a life-changing close encounter, with whom would you share that knowledge?

Most of the time, he’s able to find an explanation, he says. He often sends videos to other volunteers at MUFON who specialize in analyzing computer images. He refers to websites that track the flight patterns of satellites and planes and the International Space Station—the usual suspects when it comes to UFO sightings, he says. Guillemette described a recent case in which a couple reported seeing strange lights hovering above a nearby lake. The lights circled above the lake and then dropped down into the water, only to rise up a moment later and zip away. It turned out to be a plane, he says—filling up with water to fight a nearby forest fire. “Not everybody likes what we come up with,” he says, “but sometimes it’s really evident.”

Crowded Skies (Vaughan Yarwood, New Zealand Geographic, April 1997)

The history of UFO sightings in New Zealand dates back to the early 20th century. It seems such a tranquil and unassuming country—cinematic hobbit history notwithstanding—which perhaps makes the events recounted here even more unsettling. These are all-too-human tales of altered lives. Some cases, such as that of Iris Catt, a self-proclaimed alien abductee whose nightmarish encounters go back to her childhood, are heartbreakingly tragic. Others follow more positive narratives, believing that aliens are beaming down rays of positivity and openness, gradually bringing humanity to a point where it is ready for formal communication.

When I was at university in the 1990s, “regression therapy”  became big news, with countless stories of trauma-blocked memories and past-life remembrances unearthed through hypnosis. Just as suddenly, regression therapy drowned in a flood of peer-reviewed criticism, relegated to yet another pseudoscience. The concept never went away entirely and it pops up again in Vaughan Yarwood’s story, cautiously approved by academic institutions for its utility in specific circumstances. It’s complex territory, but Yarwood navigates it with clarity and sensitivity.

Iris Catt, a mild-mannered, unprepossessing woman in her 40s, then introduces herself. She is an abductee. It appears certain aliens have had their eye on her from an early age. She recounts her night horrors calmly, the way people do who have learned to accept their scars, to make their hurt and anguish a part of themselves.

“It is happening every day, and it is happening in New Zealand,” says Iris. “It is not going to go away. I truly believe that more and more people are beginning to remember what is happening to them because the time is getting closer when we are going to have to recognise that we are not the only intelligent form of life in the universe.”

Her audience understands. She is among friends.

Alien Nation (Ralph Blumenthal, Vanity Fair, May 2013)

Harvard Medical School psychiatrist John Edward Mack spent many years engaging with people who claimed to have been abducted by extraterrestrials, in the process becoming a pioneer in his field. Not surprisingly, he attracted resistance from the scientific community—less because of his work than because, over time, he came to the startling and highly controversial conclusion that a number of alleged abductees were telling the truth. Mack’s research may be little remembered by his profession at large, but his warmth, humanity, and faith continue to inspire hope in a small community that gathers annually in Rhode Island. They prefer the term “experiencer” to “abductee,” and in this Vanity Fair feature Ralph Blumenthal interweaves their stories with Mack’s.

For more about one of the characters in Blumenthal’s story, a 1994 feature in Omni details Linda’s alleged experience.

Once again, for me, the fascination of this piece lies in the stories of these everyday folks. To some degree, it doesn’t matter what they actually experienced. What counts, as Mack understood, is they have experienced something, and that something left a profound mark on their lives. In seeking to apply rigor and structure to the stories he was collecting, Mack plowed a hard path with poise and compassion. As this piece eloquently shows, his work was not in vain.

“Nothing in my nearly 40 years of familiarity with psychiatry prepared me,” Mack later wrote in his 1994 best-seller, Abduction: Human Encounters with Aliens. He had always assumed that anyone claiming to have been abducted by aliens was crazy, along with those who took them seriously. But here were people—students, homemakers, secretaries, writers, businesspeople, computer technicians, musicians, psychologists, a prison guard, an acupuncturist, a social worker, a gas-station attendant—reporting experiences that Mack could not begin to fathom, things, he reflected, that by all notions of reality “simply could not be.”

One Man’s Quest to Investigate the Mysterious “Wow!” Signal (Keith Cooper, Supercluster, August 2022)

I have long been fascinated with the so-called Wow signal, received in 1977 by Ohio University’s Big Ear radio telescope, which was then being used to search for evidence of extraterrestrial intelligence. The tale of the signal makes for a great story in itself, but Keith Cooper’s piece sees that as merely a starting point. His narrative finds a central character in a man named Robert Gray: While the scientific community, including SETI (the Search for Extraterrestrial Intelligence), gradually lowered the Wow signal to the status of “interesting curio,” Gray remained convinced that there was more to uncover.

Gray’s tenacity and belief in the face of mounting opposition is remarkable. Struggling for funding, unsuccessfully attempting to enlist help, and bartering for much-needed time on a limited number of radio telescopes, the frustrations he must have experienced make the twists in his story all the more poignant. Just when his enthusiasm began to wane, his work seemingly at a dead end, an exoplanet scientist reached out to Gray with a fresh idea, breathing new life into the man’s relentless quest. There is no neat, satisfying definitive end to this tale, but perhaps therein lies the true glory of Gray’s work. In the face of uncertainty, he carried on until the very end.

Nobody knows what the Wow signal was. We do know that it was not a regular astrophysical object, such as a galaxy or a pulsar. Curious the frequency that it was detected at, 1,420 MHz, is the frequency emitted by neutral hydrogen atoms in space, but it is also the frequency that scientists hunting for alien life listen to. Their reasoning is that aliens will supposedly know that astronomers will already be listening to that frequency in their studies of galactic hydrogen and so should easily detect their signal – or so the theory goes. Yet there was no message attached to the signal. It was just a burst of raw radio energy.

If SETI had a mythology, then the Wow signal would be its number one myth. And while it has never been forgotten by the public, the academic side of SETI has, by and large, dismissed it, quite possibly because it hasn’t been seen to repeat, and therefore cannot be verified—the golden rule of a successful SETI (Search for Extraterrestrial Intelligence) detection.

How Harry Reid, a Terrorist Interrogator and the Singer from Blink-182 Took UFOs Mainstream (Bryan Bender, Politico, May 2021)

Celebrities who have copped to believing in UFOs are numerous enough to populate a listicle. Politicians? Not so much. Yet, the U.S. Congress’ House Oversight Committee has announced plans for a hearing regarding UAP reports, and if you trace the conversation  back a few years, you’ll find that this shift is at least partly thanks to the protagonists in this story: former U.S. senator Harry Reid and Tom DeLonge, a founding member of pop-punk band Blink 182.

There’s a lot to digest here. It’s a wonderful example of hidden history: a small group of like-minded individuals working behind the scenes to advance their cause, with potentially wide-ranging repercussions. That history would be far less engaging, however, were it not for Tom DeLonge’s gregarious personality and indefatigable belief in alien visitors. His company, To The Stars, devotes considerable time and money to researching UAPs and extraterrestrial matters in general; Bryan Bender’s feature tells the story of how the singer managed to recruit experts and politicians to his cause.

Hanging on DeLonge’s wall was what might be considered the medals he’s collected in his struggle: a display case filled with dozens of commemorative coins from his meetings with generals, aerospace contractors and secret government agencies. They trace his visits to the CIA, to the U.S. Navy, to the “advanced development programs” division at Lockheed Martin’s famously secretive “Skunk Works” in Southern California, where some of the world’s most advanced spy planes were designed.


Chris Wheatley is a writer and journalist based in Oxford, U.K. He has too many guitars, too many records, and not enough cats.

Editor: Peter Rubin
Copy Editor: Krista Stevens

Toward a Feminist View of Harm

Oppression, Harm, and Feminist Philosophy In many ways, our understanding of oppression is closely tied to the concept of harm. This connection is especially clear in feminist philosophy—not only do feminist philosophers regularly analyze oppression’s physical, material, psychological, and social harms, but they often argue that harm is a constitutive feature of oppression. For instance, […]

On Vitamins

Molecular model of Vitamin B12. Licensed under CCO 4.0, courtesy of Wikimedia Commons.

Three years ago, I biked into a curb and fell on my head. When I got up, I couldn’t remember where I was, so I called an ambulance, which drove me to the nearest hospital, which was apparently one block away. The emergency room doctors told me there was nothing they could do. My eye was swollen, but my face seemed otherwise normal, and they wouldn’t know if anything was wrong with my brain unless they ran a CAT scan, which would expose me to toxic radiation. I asked if there were any nontoxic tests they could run for free. They offered to run a blood panel, which would let me know if I had any STIs. I let them bind my forearm, which had nothing to do with my head.

The next day, the doctor sent a message through the hospital’s online portal. My tests all came back negative, but they had also run a nutrient panel, and I was deficient in B12. I started googling. “Fell off bike low B12?” Everything that came up was random; I might as well have strung together any other combination of five words. I wanted to google more, but the doctor had told me that the internet was bad for my concussion. So I forgot about my deficiency and tried hard to make my body do nothing, which was the only way for it to heal.

Things got better. I started to feel normal, and eventually I was allowed to google as much as I wanted. Years went by. And then one day at a café, I met a man—a comedian—who told me horror stories about his life as a former vegan. His hair had fallen out, he was exhausted, his mood was always sour, and it was all because of vitamins: he could never get enough of them. While he complained, I felt my hairline receding; I was a vegan, too. And when I thought about it, really thought about it, my personality was on the decline. I was always struggling to make my days have meaning, and I wore my meaninglessness like a divine premonition. (“I have a feeling,” I texted a friend, “that something bad, really bad, is going to happen.”) I remembered the emergency room doctor’s diagnosis and felt the empty place inside of me where all the B12 supplements should have been, leeching into my bloodstream.

I tried to make a doctor’s appointment, but I had moved to California, and my insurance only covered care in New York. My body was on the West Coast, but all the tools I had for reading it were on the East. I told my father I was coming home to visit him, and when I arrived, asked him to drop me off at urgent care.

“Sorry,” said the receptionist. “The only blood work we do is for STIs. Nutrition panels aren’t urgent.”

I called my primary care physician’s office and told them that I had a need, a pressing need, for a B12 test. Everything I was feeling—daily bouts of idiocy, a persistent feeling of doom—was perfectly summarized by the deficiency symptoms I found online: headaches, psychological problems, palpitations, dementia. The receptionist told me that a nurse practitioner would be able to draw blood the next day—not soon enough. I requested a personal day from work and went to CVS, where I bought a bottle of supplements labeled “maximum strength.” Each pill contained 5,000 mcg of B12, which is 208,000 percent times the recommended daily value. They weren’t even vegan, but I took a double dose, hoping it would tide me over until my appointment, after which I was sure the doctor would put me on an emergency course of injections.

My brain was becoming an abacus. It was almost impossible to feel my feelings without translating them into the language of diagnosis, which was laughably general and yet strangely precise: symptoms claimed to contain the spectrum of human experience, but reduced that experience to a dozen ugly words. The vitamins themselves could counteract those ugly words because they contained good words of their own. Happiness, energy, valiance, relaxation: swallowing them daily felt like ingesting a little promise, saying a little prayer. How else could I communicate with my body besides putting speech inside it?

Anyway, my appointment came and went. No one called to give me my results, and when I checked the online portal, I noticed that my doctor, who hadn’t even seen me directly, who was in the habit of using the euphemisms “number one” and “number two,” had left me a message. “Hi mya—everything is looking great : ) No need for a follow-up at this time.” I checked the numbers. My B12 levels had surpassed the minimum threshold; they had even surpassed the desirable range. The pills had worked, and they had worked too well. The data, my data, had been contaminated: the language on the screen had nothing to do with what was happening in my body. And yet the doctor depended upon that language to approach my body, even though my body had been in front of her, trying to announce its problems.

I wanted the numbers to go down. Once they went down, I could prove to my doctor that they needed desperately to go back up. And so, I stopped taking the supplements, and the B12 slowly left me, detaching itself from my vocabulary until it became an abstract problem, a nonurgent problem, a random string of letters and numbers whose meaning was obscure to me, and which was no longer a metaphor for happiness.

 

Maya Binyam is a contributing editor of the Review. Her novel, Hangman, will be published by Farrar, Straus and Giroux in August.

Is a 15-week limit on abortion an acceptable compromise?

A photo of a protest sign that says "keep abortion legal" in front of the US Capitol building. "Is a 15-week limit on abortion an acceptable compromise?" by Bonnie Steinbock on the OUP blog

Is a 15-week limit on abortion an acceptable compromise?

A recent opinion piece by George F. Will, “Ambivalent about abortion, the American middle begins to find its voice” in the Washington Post made the startling claim that the overturning of Roe v. Wade (Dobbs v. Jackson Women’s Health Organization, 2022) has resulted in “a partial healing of the nation’s civic culture.” One might think exactly the reverse. The Dobbs decision energized voters, especially women and young people, resulting in numerous Republican electoral defeats across the country. However, Will argues that the return of abortion policy to the states gives voters the opportunity of choosing moderate restrictions on abortion. Since most Americans support early abortion while opposing late-gestation abortion, Will thinks that a 15-week ban on abortion would be an acceptable compromise.

Why 15 weeks? Two reasons can be given. Almost all abortions in the US—93%—occur within the first 15 weeks of pregnancy. For this reason, making abortion illegal after 15 weeks would not, it would seem, impose serious burdens on most people seeking abortions. 

Another reason is that several European countries limit abortion on request to the first trimester, leading some US lawmakers to suggest that a 15-week ban would bring our abortion law in line with theirs. This is disingenuous, to say the least. While elective abortion is limited in some European countries, it is not banned afterwards, but is allowed on other grounds, including economic or social reasons, or a threat to the woman’s physical or mental health. Moreover, in most European countries, patients do not have to pay for abortion; it is covered under universal health coverage. The fact is that the trend in Europe has not been to limit abortion, but to expand access to it. Countries in Europe “… have removed bans, increased abortion’s legality and taken steps to ensure laws and policies on abortion are guided by public health evidence and clinical best practices.”

Were states to guarantee access to abortion prior to 15 weeks, a 15-week ban might be acceptable. However, even before Dobbs, many women in the US lacked access to abortion, due to a dearth of providers, especially in rural areas. They often had to travel many miles to find an abortion clinic, which meant that they had to arrange childcare if they have other children or take time off work. Delay is also caused by the need to raise money for an abortion, which is not paid for by Medicaid in most states, except in cases of rape, incest, or a life-threatening condition. To be sure, even if there were none of these roadblocks, some women would still not be able to have early abortions because they do not know that they are pregnant, due to youth, being menopausal, chronic obesity, or a lack of pregnancy symptoms. Any time limits will pose hardships for some people. But if access to early abortions were guaranteed, a compromise on a 15-week limit might be worth it.

I suspect that time-limit advocates are not particularly interested in making sure that women who have abortions get them early in pregnancy. They want to place roadblocks in the way of getting abortions, full stop. That these roadblocks increase the numbers of late abortions is of little concern to them, however much they wring their hands over late abortions. Abortion can be reduced by reducing the number of unwanted pregnancies, something that has been shown to be achieved by access to contraceptives and science-based sex education in the schools. Remember when pro-lifers emphasized those methods? Me neither. 

“Some US lawmakers suggest that a 15-week ban would bring our abortion law in line with European countries. This is disingenuous, to say the least.”

My second concern is with abortions sought after 15 weeks. The reason for a late abortion may be that the woman has a medical condition that has not developed, or has not been detected, until later in pregnancy. In such cases, the pregnancy is almost always a wanted pregnancy, and the decision to terminate imposes a tragic choice.

It may be responded that all states allow abortions to be performed when this is necessary to save the pregnant woman’s life, and many allow for abortions to protect her from a serious health risk. The problem is that these exceptions conflict with standard medical care, especially in the case of miscarriage. Once the woman has begun to miscarry, the failure to remove the fetus is likely to cause her sepsis, which can be life-threatening. However, in states with restrictive abortion laws, doctors cannot perform an immediate abortion, which is the standard of care in such situations. They have to wait until her death is imminent and, in some states, they cannot remove the fetus until its heart stops. 

Ireland’s restrictive abortion law was repealed after a woman who was denied an abortion during a miscarriage died from septicemia. To the best of my knowledge, no woman in the US has died as a result of restrictive abortion laws, but some have come close. An OB-GYN in San Antonio had to wait until the fetal heartbeat stopped to treat a miscarrying patient who developed a dangerous womb infection. The delay caused complications which required her to have surgery, lose multiple liters of blood, and be put on a breathing machine. Texas law essentially requires doctors to commit malpractice.

Conservatives often portray those in the pro-choice camp as advocating abortion until the day of delivery, for trivial reasons. This is deeply unfair. If they want us to compromise on time limits, they should be willing to guarantee access to abortion before 15 weeks. They should be willing to compromise on pregnancy prevention through contraception and sex education. And they should agree to drop all restrictions on late-term abortions that make legislators, rather than doctors, in charge of deciding what is appropriate medical care for their patients.

Featured image: Gayatri Malhotra via Unsplash (public domain)

OUPblog - Academic insights for the thinking world.

Is Coffee Good for You?: A Coffee Connoisseur Reviews the Scientific Research

By: OC

According to NPR, “Caffeine is the most widely consumed drug in the world. Here in the U.S., according to a 2022 survey, more than 93% of adults consume caffeine, and of those, 75% consume caffeine at least once a day.” Given the prevalence of coffee worldwide, it pays to ask a simple question: Is coffee good for you? Above, James Hoffmann, the author of The World Atlas of Coffee, provides an overview of research examining the relationship between coffee and various dimensions of health, including the gut/microbiome, sleep, cancer, cognition, mortality and more. If you want to explore this subject more deeply, Hoffmann has created a list of the research papers reviewed here.

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